Chemopreventive role of Euphorbia neriifolia (linn) and its isolated flavonoid against n-nitrosodiethylamine-induced renal histopathological damage in male mice
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منابع مشابه
Chemopreventive role of Coriandrum sativum against gentamicin-induced renal histopathological damage in rats
Drug induced nephrotoxicity is one of the most common causes of renal failure. Gentamicin belongs to aminoglycosides, which elicit nephrotoxic potential. Natural antioxidants from plants demonstrate a number of biotherapeutic activities. Coriander is an important medicinal plant known for its hepatoprotective, diuretic, carminative, digestive and antihelminthic potential. This study was designe...
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Kidney cancer is the third most common malignancy of the genitourinary system account for 2 to 3 % of all cancers in men worldwide, with 130,000 new cases and 63,000 deaths from the disease occurring annually (Ferlay et al., 2004). Certain toxic chemicals and medicines can cause renal damage, are recognized as a toxicological problem. NNitrosodiethylamine (DENA) is the most important environmen...
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Background: This work aimed at studying the protective effect of melatonin (MLT) against cypermethrin or γ-radiation induced testicular damage. Material and Methods: Thirty six Male rats were randomly divided into 6 groups. Control group, group treated with MLT (10 mg/Kg b. wt.), group administered cypermethrin (25 mg/ kg. b. wt.), group 4 was exposed to fractionated whole body γ-radiation (th...
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Oxidative stress induced ROS and free radicals are believed to be major cause of degenerative diseases. Naturally occurring antioxidant supplements from plants are vital to counter the oxidative damage in cells. We assessed the antioxidant potential and phytochemical constituents of crude hydro-alcoholic extract of Euphorbia neriifolia (EN) using tests involving inhibition of DPPH, H2O2, supero...
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The objective of the present study was to investigate the hepatoprotective activity of methanol extract of Euphorbia neriifolia (MEEN) against paracetamol induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats by oral administration of paracetamol (640 mg/kg suspended in 1% carboxy methyl cellulose), once during the 16 days treatment period. MEEN was administered orally at the doses ...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2013
ISSN: 0971-6580
DOI: 10.4103/0971-6580.111554